pentobarbital will minimize the extent or outcome of clarithromycin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.
pentobarbital will reduce the level or effect of disopyramide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unidentified.
Contraindicated. Coadministration of doravirine with a powerful CYP3A inducer may lessen doravirine plasma concentrations and/or effects. Potential for lack of virologic reaction and attainable resistance to doravirine.
pentobarbital will lower the level or result of colchicine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the extent or result of dienogest/estradiol valerate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Females shouldn't pick out estradiol valerate/dienogest as their contraceptive though applying sturdy CYP3A4 inducers on account of probable lessen in contraceptive efficacy.
Stay away from; coadministration with CYP3A inducers may perhaps bring about reduced plasma concentrations of elvitegravir and/or even a concomitantly administered protease inhibitor and lead to loss of therapeutic influence and also to probable resistance
pentobarbital will lessen the extent or impact of estrogens conjugated artificial by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will decrease the extent or result of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Impact of coadministering a solid CYP3A4 inducer with fedratinib has not been analyzed.
pentobarbital will lessen the level or impact of elagolix by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will reduce the extent or effect of fentanyl intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead into a lessen in fentanyl plasma concentrations, lack of efficacy or, maybe, development of a withdrawal syndrome inside of a affected individual who may have developed Actual physical dependence to fentanyl.
pentobarbital will minimize the extent or influence of duvelisib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration with a robust CYP3A inducer decreases duvelisib place beneath the curve (AUC), which may cut down duvelisib efficacy.
pentobarbital will minimize the extent or influence of lapatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
If this drug is utilized throughout pregnancy, or Should the affected person turns into Expecting even though having this drug, the affected individual must be apprised from the potential hazard for the discover this info here fetus
pentobarbital will reduce the extent or influence of ondansetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. No dosage adjustment for ondansetron is suggested for patients on these drugs.